A second child may have been cured of HIV

Last March , Mississippi doctors announced that early and belligerent treatment ofan HIV - positive newborn had cure the youngster of her infection . Today , Los Angeles doctors cover that a 2nd child may have been cured by a exchangeable course of instruction of treatment , and could aid prove that the Mississippi minor ’s recovery was more than a separatrix of luck .

HIV has been cured in a tiddler for the first time

Above : An SEM microcraph of HIV-1 bud from cultured lymphocyte

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The case was presented today by doctor at at the 21st annual Conference on Retroviruses and Opportunistic Infections in Boston ( last yr ’s announcement fall at the twentieth annual CROI).Via the Associated Press :

The young woman was born in suburban Los Angeles last April , a month after researchers announced the first grammatical case from Mississippi .

That case was a medical first that lead doctors worldwide to rethink how tight and hard to treat infants bear with HIV . The California doctors follow that example .

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The Mississippi baby is now 3 1/2 and seems HIV - free despite no treatment for about two years . The Los Angeles baby is still stupefy AIDS medicament , so the status of her transmission is not as absolved .

A host of advanced tests at multiple times indicate the LA baby has completely cleared the virus , said Dr. Deborah Persaud , a Johns Hopkins University physician who led the examination [ Ed . Note : Persaud was the atomic number 82 author of the reputation recounting the Mississippi nipper ’s intervention at last yr ’s league on Retroviruses and Opportunistic Infections ] . The child ’s signs are different from what doctors see in patient whose infections are but suppressed by successful treatment , she said .

“ We do n’t know if the baby is in remitment … but it looks like that , ” say Dr. Yvonne Bryson , an infectious disease specializer at Mattel Children ’s Hospital UCLA who consulted on the girl ’s fear .

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Doctors are cautious about indicate she has been heal , “ but that ’s obviously our Bob Hope , ” Bryson say .

Both kid were stomach to HIV - confirming mother , neither of whom had taken the medications , typically lot during such pregnancies , that reduce the chances of pass the virus on to newborn baby . Both shaver were come out on an fast-growing antiretroviral intervention just hour after birth , too early for tests to bring out whether the newborns had actually been infect by their HIV - confirming mother ( both , doctors in each illustration later learned , had ) ; and followup test in both situations suggest the child had crystallize their systems of the computer virus . One major difference : The Mississippi little girl was process until she was 18 calendar month honest-to-goodness , when Dr. lost liaison with her ( when she returned ten months late , doctors found not trace of the infection in blood exam ) ; the Los Angeles girlfriend , however , is still being address and cautiously monitored .

It ’s encourage how much the two cases have in common ; if the ongoing discourse in the Los Angeles case proves successful , it could help prove that that the Mississippi subject was no trematode worm . But even if the Los Angeles child does come away functionally cured of HIV , research worker will obviously require more than two cause to make early and aggressive retroviral intervention as a standard therapy for babies at risk of HIV - infection . To that end , Bryson is heading up a discipline that will probe whether such discussion can , in fact , heal HIV contagion in newborn baby . The study will reportedly involve about 60 newborn infant , from the U.S. and other state , who will find belligerent treatment for their first two years of life , only to have that intervention quit should trace of active infection cease to come out in blood samples .

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