The short answer ? An perfectly mirthful amount , perhaps lit by a jet railway locomotive . It would also aid if you owned a residence in Toontown or were physically a Tex Avery illustration . In a1988 DEA brief , Judge Francis Young did the mathematics and relegate down just how much sticky - stinking it would take to off you totally :
It is estimated that marijuana ’s [ median lethal dose ] is around 1:20,000 or 1:40,000 . In layman footing this means that in rules of order to induce death a marihuana stag party would have to squander 20,000 to 40,000 clip as much marijuana as is contained in one marijuana cigarette . [ National Institute on Drug Abuse]-supplied marijuana coffin nail weigh about .9 Hans C. J. Gram . A smoker would theoretically have to consume almost 1,500 pounds of marijuana within about fifteen minutes to make a lethal response .
Young goes on to suspect , “ In pragmatic footing , marijuana can not induce a deadly response as a result of drug - interrelate perniciousness . ” But what if you actually wanted to , in completely visionary full term ? I imagine that you would have to build a hotbox the size of a zikurat and ignite your stash via orbital optical maser .

ViaDangerous Minds . Top song — Scientist ’s “ Your Teeth In My Neck ” fromScientist Rids the World of the Evil Curse of the Vampires — because I wanted to hear to it .
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